Autores: Ana Santurtún | Alejandro Villar | Laura López-Delgado | Javier Riancho
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease (ND) affecting motor neurons (1–3 cases per 100,000 habitants) [1]. Although ALS pathogenesis remains unclear, the most accepted theory postulates that genes and environment interact
leading to the disease onset in predisposed individuals [2,3]. Regarding richness, its influence has been previously studied in a wide number
of NDs, such as Alzheimer’s disease [4]. In these studies, richness was negatively correlated with the incidence of dementia. Differently from
the rest of NDs, the role of richness in ALS has not been directly assessed yet. In this study, we explored the relationship between the gross domestic product (GDP) and the incidence of ALS in Spain between 2000 and 2011. […]